S Narasimha Murthy, Howard I. Maibach's Topical Nail Products and Ungual Drug Delivery PDF

By S Narasimha Murthy, Howard I. Maibach

ISBN-10: 1439811296

ISBN-13: 9781439811290

Discussing latest ideas, ongoing study, new techniques, and simple ideas within the therapy of nail illnesses, Topical Nail items and Ungual Drug supply summarizes the present wisdom and represents a jumping-off aspect for growing novel options of drug supply around the nail.

A transforming into zone of pharmaceutical examine, the quest for effective supply ideas that could pass the nail barrier has yielded a number of powerful options, introduced jointly during this book.

Topics Include

  • Nail anatomy, body structure, illnesses, and treatment
  • Permeability of the nail plate
  • Topical nail formulations
  • Approaches to reinforce ungual and trans-ungual drug delivery
  • In vitro and in vivo versions to guage topical nail formulations
  • Nail sampling techniques
  • Bioengineering of the nail
  • Trans-ungual iontophoresis
  • Pharmacokinetics of substances within the nail apparatus
  • Onychopharmacokinetics: proposed version insight
  • Photodynamic remedy of nail diseases
  • The nail as a surrogate for investigating drug use

Show description

Read Online or Download Topical Nail Products and Ungual Drug Delivery PDF

Similar pharmacy books

New PDF release: Pharmaceutical Dosage Forms: Vol. 2 - Parenteral

This three-volume set of Pharmaceutical Dosage kinds: Parenteral drugs is an authoritative, entire reference paintings at the formula and manufacture of parenteral dosage types, successfully balancing theoretical issues with the sensible points in their improvement. As such, it's endorsed for scientists and engineers within the pharmaceutical and academia, and also will function an exceptional reference and coaching software for regulatory scientists and caliber coverage pros.

Download e-book for kindle: Successful Strategies for the Discovery of Antiviral Drugs by Manoj C. Desai, Nicholas A. Meanwell, David E Thurston,

A quantity that might be aimed toward medicinal chemistry and rising drug discovery scientists. The ebook can be geared up based on many of the recommendations deployed for the invention and optimization of preliminary lead compounds. will probably be damaged down into 4 major sections: phenotypic and biochemical screening, constitution and actual property-based drug layout and supply of antiviral brokers.

The Tetracyclines - download pdf or read online

The historical past of antibiotics might weIl have started with the traditional Sudanese-Nubian civilization (see bankruptcy 1, "Historical Introduction"), yet this quantity displays a extra modern appraisal of the antibiotic period. now we have compiled a entire overview of the tetracyclines together with the entire significant sub­ divisions of those chemically very important and clinically important antibiotics.

Download e-book for iPad: Topical Nail Products and Ungual Drug Delivery by S Narasimha Murthy, Howard I. Maibach

Discussing present strategies, ongoing examine, new techniques, and uncomplicated recommendations within the remedy of nail illnesses, Topical Nail items and Ungual Drug supply summarizes the present wisdom and represents a jumping-off aspect for developing novel options of drug supply around the nail. A growing to be zone of pharmaceutical study, the quest for effective supply ideas which can move the nail barrier has yielded numerous powerful recommendations, introduced jointly during this e-book.

Extra info for Topical Nail Products and Ungual Drug Delivery

Example text

Archives of Dermatological Research 258 (1): 94. Gilchrist, M. , and L. H. Dudley Buxton. 1939. ” Journal of Anatomy 73: 575–82. , O. F. Nielsen, D. H. Christensen, and H. C. Wulf. 1998. ” Journal of Investigative Dermatology 110 (4): 393–98. Gonzalez-Serva, A. 1997. ” In Nails: Therapy, Diagnosis, Surgery, edited by R. K. Scher and C. R. Daniel. Philadelphia: WB Saunders. , and G. B. Kasting. 2006. ” Journal of Cosmetic Science 57 (2): 183–84. Gunt, H. , and G. B. Kasting. 2007. ” European Journal of Pharmaceutical Sciences 32 (4–5): 254–60.

Keratin binding becomes beneficial for therapy by providing a drug reservoir in the nail plate, such that systemic treatment can be given in pulses. On the other hand, during topical therapy, the drug penetrates the nail plate following application to its dorsal surface—a very good barrier to drug penetration. Keratin binding to the small amounts of drug that permeated into the nail plate could result in insufficient free drug available for antifungal activity. Drug binding to keratin in this case would have an adverse effect on antifungal activity.

Gonzalez-Serva, A. 1997. ” In Nails: Therapy, Diagnosis, Surgery, edited by R. K. Scher and C. R. Daniel. Philadelphia: WB Saunders. , and G. B. Kasting. 2006. ” Journal of Cosmetic Science 57 (2): 183–84. Gunt, H. , and G. B. Kasting. 2007. ” European Journal of Pharmaceutical Sciences 32 (4–5): 254–60. Gupchup, G. , and J. L. Zatz. 1999. ” Journal of Cosmetic Science 50 (6): 363–85. Gupta, A. , and L. E. Lynch. 2004. ” Cutis 74 (1): 5–9. Gupta, A. , and N. H. Shear. 1997. ” Canadian Family Physician 43: 299–305.

Download PDF sample

Topical Nail Products and Ungual Drug Delivery by S Narasimha Murthy, Howard I. Maibach


by Thomas
4.3

Rated 4.95 of 5 – based on 12 votes