Ray Spangenburg's Barbara McClintock: Pioneering Geneticist (Makers of Modern PDF

By Ray Spangenburg

ISBN-10: 0816061726

ISBN-13: 9780816061723

Barbara McClintock was once a celebrated geneticist whose 70 years of meticulous experiments within the genetics of maize, or Indian corn, were lauded for his or her contributions to latest such a lot state-of-the-art expertise and technology, together with genetic engineering and bacterial reactions to antibiotics. Winner of the 1983 Nobel Prize in body structure or drugs, she first took an interest in genetics whereas learning at Cornell college within the Nineteen Twenties. The threads of McClintock's notable paintings, woven opposed to deep-rooted prejudices that regularly made investment tricky to achieve, and sustained every now and then in simple terms by way of her deep point of dedication and backbone, shape the backdrop of this dramatic new biography. Crisply written and illustrated, "Barbara McClintock" illuminates the struggles and achievements of 1 of an important clinical minds of our time.

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Extra info for Barbara McClintock: Pioneering Geneticist (Makers of Modern Science)

Sample text

And I couldn’t take it.  . I just couldn’t stand that kind of discrimination. ” McClintock is believed to have lived alone most of her life and she liked to point out, as she did to Evelyn Keller, that she never felt the need for day-to-day live-in companionship. ” “These attachments wouldn’t have lasted,” she stressed in an interview with Evelyn Fox Keller. McClintock recognized that she was not constructed to fit into someone else’s life. “There was not that strong necessity for a personal attachment to anybody,” she continued.

By making a few wizardly adjustments to improve the clarity of results for maize, she succeeded in gathering a highly viewable sample of every chromosome at each stage of cell division and replication in both mitotic and meiotic chromosomes. By 1929–30, she also had the idea of looking at the process of cell division during the pachytene stage of meiosis. During this stage, in certain strains of corn, the chromosomes are more slender and stretched out and less condensed. McClintock found that the chromosomes were much easier to study before they became so dense.

Flowering plants (such as the garden peas grown by Mendel and McClintock’s maize) undergo meiosis in the sporophyte phase (a spore-producing diploid [2n] stage) to produce haploid spores. This process is called sporogenesis. Haploid spores (n, the products of meiosis) divide by mitosis and develop into a gamete-producing stage or phase called a gametophyte (n). Haploid gametophytes undergo mitosis to produce gametes (sex cells, n). This process is called gametogenesis. Haploid gametes (male or female sex cells) may fuse with a gamete from another gametophyte to form diploid zygotes (2n).

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Barbara McClintock: Pioneering Geneticist (Makers of Modern Science) by Ray Spangenburg


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