By Prof. Dr. Wolfgang Leistenschneider, Prof. Dr. Reinhard Nagel (auth.)
Diagnostic and exfoliative cytology has this day completed a standing that few can have envisaged twenty years in the past. whereas exfoliative cytology has lengthy been hired in gynecological analysis, new and lucrative spheres have now constructed within which cytological analysis performs a tremendous position. Exfoliative cytology, for instance, is generally hired as an relief within the non-stop review of urinary tract tumors, and aspiration cytology within the analysis of thyroid dis eases. This has given upward thrust to a starting to be call for for pathologists skilled in cytological prognosis. besides the fact that, clinicians with an curiosity in morphology have been usually the 1st to undertake those uncomplicated and secure equipment, being clearly attracted by way of the opportunity to prevent carrying out biopsy, which, within the final research, is not anything below a surgical procedure. during this Atlas of Prostatic Cytology Leistenschneider and Nagel expertly reveal what might be completed while clinicians expert in morphology take an curiosity in cytological tools. not just have they got direct touch with the sufferer, yet in addition they cash in on instantly being capable of determine the result of their diagnostic methods via studying the specimen got. From the technical standpoint aspiration biopsy of the prostate is under no circumstances an easy approach and the problems concerned would appear to were underestimated within the preliminary part of enthusiastic acclaim. therefore it's been commonplace for clinicians and pathologists to be dissatisfied by way of the excessive expense of unsatisfactory samples received by means of this method.
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Extra resources for Atlas of Prostatic Cytology: Techniques and Diagnosis
45. Sheet of seminal vesicle cells with only moderate nuclear polymorphism and a 'paving stone' appearance of the nuclei. No prominent nucleoli. Typical pigment granules. x 630 Fig. 46. Aspirate with admixture of stool. Small sheet of prostatic epithelium at the upper right of the picture. x 400 Fig. 47 a. Tangentially smeared sheet of cells from the rectal mucosa. Local balloon-like vacuolation of the cytoplasm of the goblet cells. Small, round to oval nuclei with clearly defined nuclear membrane.
X 630 Fig. 46. Aspirate with admixture of stool. Small sheet of prostatic epithelium at the upper right of the picture. x 400 Fig. 47 a. Tangentially smeared sheet of cells from the rectal mucosa. Local balloon-like vacuolation of the cytoplasm of the goblet cells. Small, round to oval nuclei with clearly defined nuclear membrane. x400 56 Fig. 47b. Same sheet at higher magnifica- tion: the exceedingly thick nuclear membranes are clearly seen. Loose chromatin structure; typical coffee-bean shape of the nuclei in places.
6 Sheets of Keratin (Fig. 56) Benign metaplastic squamous epithelial cells should not be mistaken for sheets of keratin, which stem from the peri-anal area of the rectum, stain yellowish-orange, and are anucleate (Fig. 56). 7 Histiocytic Giant Cells (Figs. 57-59) The often considerable size of the histiocytes and their wealth of nuclei may mimic groups of epithelial cells from a prostatic carcinoma, especially during treatment. Isolated histiocytic giant cells in the prostate are invariably an expression of a strong resorptive reaction to inflammatory disorders or surgical procedures on the prostate.
Atlas of Prostatic Cytology: Techniques and Diagnosis by Prof. Dr. Wolfgang Leistenschneider, Prof. Dr. Reinhard Nagel (auth.)