Download e-book for iPad: Analytical Profiles of Drug Substances, Excipients, and by Klaus Florey (editor)

By Klaus Florey (editor)

ISBN-10: 0122608194

ISBN-13: 9780122608193

Even though the legitimate compendia outline a drug substance as to id, purity, energy, and caliber, they usually don't supply different actual or chemical info, nor do they record equipment of synthesis or pathways of actual or organic degradation and metabolism. Such info is scattered throughout the clinical literature and the records of pharmaceutical laboratories. "Analytical Profiles of Drug ingredients" brings this data jointly into one resource.

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J. Smith, B r . J. C l i n . , 9, 395 (1980). Oh, J. Pharm. , 28, 40. M. S. 449 (1976). 25 26 ROBERT T. FOSTER AND ROBERT A. CARR 41. T. Foster, M. T. Kappagoda and F. Jarnal i , Pharm. R e s . , submitted (1990). 42. G. Bianchette, C. Dubruc, P. J. L. Morselli, C l i n . Pharmacol. T h e r . , 29, 233 (1981). 43. R. B. J. Kendall, Br. J. Clin. , 12, 427 (1981). ANALYTICAL PROFILE OF AMOBARBITAL Neelofur Abdul Aziz Mian Fahad J. O. Box 10219, Riyadh-11433, Saudi Arabia. O. Box 2457, Riyadh-11451, Saudi Arabia.

H. Summers, Am. , 109, 1211 (1985). 10. F. F. C o l l i n s , Br. J. Clin. , 2, 49 (1975). 11. B. Gourmel, J. F. M. V i l l e t t e and C Dreux, Clin. Chim. , 108, 229 (1980). 12. G. Musumarra, G. S c a r l a t a and G. Cirma, J. , 350, 151, (1985). 13. B. Jack, S. J. Kendall, J. , 187, 277 (1980). 14. M. G. A. Maes, J. , 488, 357 (1989). 15. J. R. Harapat and C. H a r r i s o n , Res. Comm. Chem. Path. , 15, 31 (1976). 16. R. J. B. Poet, J. Pharm. , 70, 336 (1981). 17. W. M. A. L. Combs and S.

4 t i g h t petroleui Paper exposed t o amionia vapour and then UV 254 n i , 17 No. 12UzO) and dried, Table 7: Summary of conditions used for GC of amylobarbitone - Column support Mesh C-lass column (3 ft X 2 m m ) of 10% of UCW982. 8 m X 4 mm) packed with 3% of SP-2250 DA 100-120 210-240 Borosilicate-glass column packed with 10% of SE-30 on Chromosorb W AW- -- 180' DMCS . Flow rate Sample Reference -- Blood 19 Nz carrier Plasma 20 gas 40 ml/ min. a -- -- 21 Liver tissues 22 Continued (Table 7 .

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Analytical Profiles of Drug Substances, Excipients, and Related Methodology by Klaus Florey (editor)

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