By Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Mario Ulises Pérez-Zepeda
This ebook experiences classical epidemiological and scientific examine experiences, with a spotlight on getting older. Chapters conceal methodological issues just like the medical approach, ethics, and the results of convinced exclusion standards and the paintings features a examine medical techniques like multi morbidity, frailty and performance. The authors display the problems and demanding situations for researchers of age and getting older, and likewise examine the interpretation of medical wisdom, from easy to scientific and from medical to public regulations of social and health and wellbeing care.
The specialize in getting older is what provides this publication its worthy point of view on examine technique. All authors have massive event in getting older, geriatrics or gerontology and every bankruptcy contains either a theoretical framework and useful examples of experiences in getting older. Readers will observe examine designs which are reviewed for uncomplicated constitution, major flaws and benefits and are analyzed for particular stipulations and variables concerning aging.
This textual content is suited for either future health care execs taking care of older adults and researchers who're new to investigate in getting older. it really is correct around the disciplines, together with drugs, psychology, social sciences and dentistry and it helps studying with graphs and figures.
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Extra resources for Aging Research - Methodological Issues
1016/S0140-6736(05)67424-7 38 E. López-Muñoz 74. David DC, Ollikainen N, Trinidad JC, Cary MP, Burlingame AL, Kenyon C (2010) Widespread protein aggregation as an inherent part of aging in C. elegans. PLoS Biol 8(8):e1000450. 1000450 75. Siwy J, Vlahou A, Zimmerli LU, Zurbig P, Schiffer E (2011) Clinical proteomics: current techniques and potential applications in the elderly. Maturitas 68(3):233–244. 1016/j. 001 76. Patti GJ, Tautenhahn R, Johannsen D, Kalisiak E, Ravussin E, Bruning JC et al (2014) Metaanalysis of global metabolomic data identifies metabolites associated with life-span extension.
There is a growing need of delimiting the dimension of conditions such as frailty, sarcopenia, cognitive decline among others; in order to alert both general public and in particular health professionals. On the other hand, smaller studies such as case series and case reports are needed in this age group to continuously describe diseases or other conditions that in the past were thought not to happen in older adults. Therefore this designs aid in increasing the recognition of health problems in older adults and the magnitude of them.
Metabolomics 10(4):737–743. 1007/s11306-013-0608-8 77. Kundu ST, Slack FJ (2010) Robust and specific inhibition of microRNAs in Caenorhabditis elegans. J Biol 9(3):20. 1186/jbiol230 78. Ido Y, Duranton A, Lan F, Weikel KA, Breton L, Ruderman NB (2015) Resveratrol prevents oxidative stress-induced senescence and proliferative dysfunction by activating the AMPKFOXO3 cascade in cultured primary human keratinocytes. PLoS One 10(2), e0115341. 0115341 Chapter 4 Descriptive Studies Mario Ulises Pérez-Zepeda and Lorena Jocabed Rocha-Balcázar Abstract Descriptive studies are a group of designs that even they have a lot of limitations, in aging are particularly important to define the different conditions that affect older adults and are not well recognized or still are in very preliminary stages.
Aging Research - Methodological Issues by Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Mario Ulises Pérez-Zepeda